Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.49 |
| ▸ | PPARA | Q07869 | 9/20 | 0.45 |
| ▸ | PPARG | P37231 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 5/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589710 | 0.98 | FFAR1 (0.50) | FFAR1PPARAPPARGKDM4EALDH1A1 | |
| SCHEMBL5379026 | 0.89 | FFAR1 (0.48) | FFAR1PPARAPPARGKDM4EALDH1A1 | |
| SCHEMBL5385319 | 0.88 | PPARA (0.49) | FFAR1PPARAPPARGKDM4EALDH1A1 | |
| SCHEMBL5377697 | 0.88 | FFAR1 (0.61) | FFAR1PPARAPPARGKDM4EALDH1A1 | |
| SCHEMBL5377119 | 0.87 | ALDH1A1 (0.45) | PPARAKDM4EALDH1A1POLBRXFP1 | |
| SCHEMBL7546657 | 0.86 | PPARA (0.46) | FFAR1PPARAPPARGKDM4EALDH1A1 | |
| SCHEMBL5377121 | 0.85 | ALDH1A1 (0.44) | PPARAPPARGKDM4EALDH1A1POLB | |
| SCHEMBL6829766 | 0.85 | FFAR1 (0.50) | FFAR1PPARAPPARGMAPT | |
| SCHEMBL5397484 | 0.84 | FFAR1 (0.48) | FFAR1PPARAPPARGKDM4EALDH1A1 | |
| SCHEMBL6829769 | 0.84 | FFAR1 (0.51) | FFAR1PPARAPPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1457490-A1 | 5-membered N-heterocyclic compounds with hypoglycemic and hypolipidemic activity | Takeda Chemical Industries, Ltd. (JP) | 2004-09-15 | — | — | EP | disclosed |
| EP-1228067-B1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-07-14 | — | — | EP | disclosed |