Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 9/20 | 0.31 |
| ▸ | CA2 | P00918 | 9/20 | 0.31 |
| ▸ | CA9 | Q16790 | 8/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA3 | P07451 | 2/20 | 0.30 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | CA6 | P23280 | 2/20 | 0.30 |
| ▸ | CA5A | P35218 | 2/20 | 0.30 |
| ▸ | CA7 | P43166 | 2/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4765474 | 0.83 | KDM4E (0.54) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL4598314 | 0.82 | ALDH1A1 (0.64) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL1207739 | 0.78 | USP2 (0.58) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL4767210 | 0.78 | KDM4E (0.58) | USP2TSHRKDM4EALDH1A1LMNA | |
| Busulfan SCHEMBL21693608 | 0.77 | TSHR (0.79) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL4768788 | 0.76 | TSHR (0.56) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL4767818 | 0.76 | TSHR (0.56) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL4767388 | 0.76 | TSHR (0.56) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL4745492 | 0.76 | TSHR (0.61) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL11343814 | 0.76 | ALDH1A1 (0.68) | USP2TSHRKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823423-B1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| CN-1188471-A | 1,4-disubstituted piepridine derivatives | BANYU PHARMA CO LTD (JP) | 1998-07-22 | — | — | CN | disclosed |
| US-5750540-A | SIDE EFFECT REDUCTION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0823423-A1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |