Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 1.00 |
| ▸ | PPARG | P37231 | 7/20 | 1.00 |
| ▸ | PPARD | Q03181 | 7/20 | 1.00 |
| ▸ | PPARA | Q07869 | 7/20 | 1.00 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 1.00 |
| ▸ | TSHR | P16473 | 4/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 3/20 | 1.00 |
| ▸ | FABP4 | P15090 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | TLR2 | O60603 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 1.00 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | ESR1 | P03372 | 1/20 | 1.00 |
| ▸ | PDE4A | P27815 | 1/20 | 1.00 |
| ▸ | PDE3A | Q14432 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lignoceric Acid SCHEMBL25290912 | 1.00 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Sebacic Acid SCHEMBL23781711 | 1.00 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL25293218 | 1.00 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dotriacontanoic Acid SCHEMBL25298401 | 1.00 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexacosanoic Acid SCHEMBL25287701 | 1.00 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL25291231 | 1.00 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL25288166 | 1.00 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Behenic Acid SCHEMBL25281884 | 1.00 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL25286532 | 1.00 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL25287435 | 1.00 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 1378254 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6361980-B1 | — | — | None | — | — | US | claimed |
| US-9974992-B2 | Fire extinguishing composition comprising carboxylic acid derivative | XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) | 2018-05-22 | — | — | US | claimed |
| US-9975220-B2 | Hand-held conformable sanding block | TRADE ASSOCIATES, INC. (US) | 2018-05-22 | — | — | US | claimed |
| US-9974726-B2 | Gentle cleansing compositions with makeup removal properties | L'OREAL (FR) | 2018-05-22 | — | — | US | claimed |
| US-9976028-B2 | Curable coating compositions of silane functional polymers | KING INDUSTRIES (US) | 2018-05-22 | — | — | US | claimed |
| US-9975006-B2 | Golf balls containing layers made from transparent polyamide and plasticizer compositions | ACUSHNET COMPANY (US) | 2018-05-22 | — | — | US | claimed |
| US-9974719-B2 | Solid cosmetic makeup and/or care composition | L'OREAL (FR) | 2018-05-22 | — | — | US | claimed |
| US-9975847-B2 | Amino acid derivatives and their uses | JOHNSON & JOHNSON CONSUMER INC. (US) | 2018-05-22 | — | — | US | claimed |
| US-9974859-B2 | Nanostructured gels capable of controlled release of entrapped agents | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2018-05-22 | — | — | US | claimed |
| US-9974402-B2 | Thermal receptacle with phase change material | BOOSKA RAYMOND (US) | 2018-05-22 | — | — | US | claimed |
| US-3952079-A | Process of releasing polyurethane foams using aluminum salts of fatty acid mixtures | HENKEL & CIE G.M.B.H. (DT) | 1976-04-20 | — | — | US | claimed |
| US-3951825-A | ORGANIC ESTERS | EASTMAN KODAK COMPANY (US) | 1976-04-20 | — | — | US | claimed |
| US-3950258-A | SALT OF SULFURIC ESTER OF POLYOXYALKYLENE COMPOUND | SANYO CHEMICAL INDUSTRIES, LTD. (JA) | 1976-04-13 | — | — | US | claimed |
| US-3947550-A | Method of making a silicon carbide article of less than full density | FORD MOTOR COMPANY (US) | 1976-03-30 | — | — | US | claimed |
| US-3946135-A | CROSSLINKING, THERMOSETTING RESINS, POLYHYDRIC ALCOHOLS | SCOTT PAPER COMPANY (US) | 1976-03-23 | — | — | US | claimed |
| US-3945404-A | Meat casing with internal release coating | TOWA KAKO CO., LTD. (JA) | 1976-03-23 | — | — | US | claimed |
| US-3946122-A | EMULSIONS, CRYSTALLIZATION | LEVER BROTHERS COMPANY (US) | 1976-03-23 | — | — | US | claimed |
| US-3937811-A | COPOLYMER | SOCIETE ANONYME DITE: L'OREAL (FR) | 1976-02-10 | — | — | US | claimed |
| US-3936391-A | Hydrated polyglycerol ester composition | DRACKETT COMPANY (US) | 1976-02-03 | — | — | US | claimed |
| US-3935141-A | METAL SALT, ANTIOXIDANT | UNION CARBIDE CORPORATION (US) | 1976-01-27 | — | — | US | claimed |