Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 12/20 | 0.65 |
| ▸ | MMP3 | P08254 | 12/20 | 0.65 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.45 |
| ▸ | CDK9 | P50750 | 4/20 | 0.45 |
| ▸ | QDPR | P09417 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590023 | 0.91 | MMP2 (0.77) | MMP2MMP3CCNT1CDK9QDPR | |
| SCHEMBL6586576 | 0.87 | MMP2 (0.80) | MMP2MMP3 | |
| SCHEMBL6586433 | 0.87 | MMP2 (0.85) | MMP2MMP3CCNT1CDK9 | |
| SCHEMBL6584172 | 0.86 | MMP2 (0.61) | MMP2MMP3CCNT1CDK9 | |
| SCHEMBL6584461 | 0.85 | MMP2 (0.65) | MMP2MMP3CCNT1CDK9 | |
| SCHEMBL6590114 | 0.84 | MMP2 (0.58) | MMP2MMP3 | |
| SCHEMBL6587364 | 0.84 | MMP2 (0.63) | MMP2MMP3CCNT1CDK9QDPR | |
| SCHEMBL6587634 | 0.84 | MMP2 (0.82) | MMP2MMP3CCNT1CDK9 | |
| SCHEMBL6588399 | 0.84 | MMP2 (0.59) | MMP2MMP3CCNT1CDK9 | |
| SCHEMBL6590460 | 0.84 | MMP2 (0.72) | MMP2MMP3CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |