Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 18/20 | 0.73 |
| ▸ | F10 | P00742 | 12/20 | 0.73 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590683 | 0.94 | F2 (0.83) | F2F10KLKB1 | |
| SCHEMBL6593016 | 0.91 | F2 (0.88) | F2F10KLKB1 | |
| SCHEMBL6592658 | 0.88 | F2 (0.77) | F2F10KLKB1 | |
| SCHEMBL6589579 | 0.88 | F2 (0.74) | F2F10KLKB1 | |
| SCHEMBL6591182 | 0.86 | F2 (0.74) | F2F10KLKB1 | |
| SCHEMBL6592013 | 0.85 | F2 (0.81) | F2F10KLKB1 | |
| SCHEMBL6595017 | 0.84 | F10 (0.66) | F2F10KLKB1 | |
| SCHEMBL6593142 | 0.84 | F2 (0.78) | F2F10 | |
| SCHEMBL6591411 | 0.84 | F2 (0.80) | F2F10KLKB1 | |
| SCHEMBL6592059 | 0.84 | F2 (1.00) | F2F10KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040108-B1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-6498185-B1 | ENZYME FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. | 2002-12-24 | — | — | US | disclosed |
| US-6380221-B1 | FOR THERAPY OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY | BERLEX LABORATORIES, INC. | 2002-04-30 | — | — | US | disclosed |
| US-6140351-A | FOR TREATING THROMBOSIS | BERLEX LABORATORIES, INC. (US) | 2000-10-31 | — | — | US | disclosed |