Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.83 |
| ▸ | F10 | P00742 | 11/20 | 0.83 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.59 |
| ▸ | ELANE | P08246 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590630 | 0.94 | F2 (0.73) | F2F10KLKB1 | |
| SCHEMBL6592013 | 0.91 | F2 (0.81) | F2F10KLKB1ELANE | |
| SCHEMBL6591411 | 0.91 | F2 (0.80) | F2F10KLKB1ELANE | |
| SCHEMBL6592059 | 0.91 | F2 (1.00) | F2F10KLKB1ELANE | |
| SCHEMBL6593127 | 0.90 | F2 (0.79) | F2F10 | |
| SCHEMBL6591645 | 0.89 | F10 (0.81) | F2F10 | |
| SCHEMBL6593142 | 0.89 | F2 (0.78) | F2F10 | |
| SCHEMBL6593866 | 0.89 | F2 (0.78) | F2F10KLKB1 | |
| SCHEMBL6591618 | 0.88 | F2 (0.84) | F2F10KLKB1ELANE | |
| SCHEMBL6592486 | 0.88 | F2 (0.87) | F2F10KLKB1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040108-B1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AG (DE) | 2004-02-25 | — | — | EP | claimed |
| EP-1337251-B1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2008-08-20 | — | — | EP | disclosed |
| CN-1143855-C | I (ortho)-anthranilamide derivatives as anti-coagulants | ���ֹɷݹ�˾ | 2004-03-31 | — | — | CN | disclosed |
| EP-1040108-B1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-6498185-B1 | ENZYME FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. | 2002-12-24 | — | — | US | disclosed |
| US-6380221-B1 | FOR THERAPY OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY | BERLEX LABORATORIES, INC. | 2002-04-30 | — | — | US | disclosed |
| CN-1282329-A | I (ortho)-anthranilamide derivatives as anti-coagulants | SCHERING AG (DE) | 2001-01-31 | — | — | CN | disclosed |
| US-6140351-A | FOR TREATING THROMBOSIS | BERLEX LABORATORIES, INC. (US) | 2000-10-31 | — | — | US | disclosed |