Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.54 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.54 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.54 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.54 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.54 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28012695 | 0.93 | NPC1 (0.65) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL10559396 | 0.90 | NPC1 (0.67) | NPC1RAB9ASLC5A1SLC5A2KDM4E | |
| SCHEMBL30572 | 0.86 | TDP1 (0.77) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL15524969 | 0.86 | TDP1 (0.77) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL28251466 | 0.86 | TDP1 (0.77) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL4485908 | 0.84 | RAB9A (0.69) | NPC1RAB9ATDP1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL27556767 | 0.84 | TDP1 (0.74) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL657122 | 0.83 | FFAR1 (0.69) | NPC1RAB9ATDP1CASP3SENP8 | |
| Alcohol SCHEMBL11308928 | 0.83 | NPC1 (0.67) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL1985867 | 0.83 | NPC1 (0.62) | NPC1RAB9ATDP1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100368386-C | Method for synthesizing (+/-) p-fluoro-2- (2-methyl-propionyl) -4-oxy-N, 3-diphenyl-phenylbutylamide and intermediate thereof | INST OF MEDICAL MATERIALS CHIN (CN) | 2008-02-13 | — | — | CN | claimed |
| CN-1325844-A | Novel synthesis method of (+/-) p-fluoro-2- (2-methyl-propionyl) -4-oxo-N, 3-diphenyl-phenylbutylamide and intermediate thereof | INST OF MEDICAL MATERIALS CHIN (CN) | 2001-12-12 | — | — | CN | claimed |
| CN-116102430-B | Alkylation synthesis method for in-situ catalytic alcohols | 中山大学 | 2025-03-14 | — | — | CN | disclosed |
| CN-116102430-A | Alkylation synthesis method for in-situ catalytic alcohols | 中山大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-112047797-B | Method for preparing alpha-alkyl substituted ketone compound | 赣南医学院 | 2023-04-07 | — | — | CN | disclosed |
| CN-111807971-B | Alkylation synthesis method for in-situ catalysis of alcohols | 中山大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-112500270-B | Method for synthesizing alpha, alpha-difluoroketone compound | 台州学院 | 2023-03-07 | — | — | CN | disclosed |
| CN-112500270-A | Method for synthesizing alpha, alpha-difluoroketone compound | 台州学院 | 2021-03-16 | — | — | CN | disclosed |
| CN-112047797-A | Method for preparing alpha-alkyl substituted ketone compound | 赣南医学院 | 2020-12-08 | — | — | CN | disclosed |
| CN-111807971-A | Alkylation synthesis method for in-situ catalysis of alcohols | 中山大学 | 2020-10-23 | — | — | CN | disclosed |
| CN-106478395-B | A kind of method of iridium catalyzed synthesizing alpha-alkyl ketone | 南京理工大学 | 2019-06-25 | — | — | CN | disclosed |
| EP-0729463-B1 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE DAVIS & CO (US) | 2002-05-22 | — | — | EP | disclosed |
| EP-1142887-A1 | 5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents | PARKE, DAVIS & COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5936128-A | BENZENETHIOL COMPOUNDS AS INTERMEDIATES; BACTERICIDES, VIRICIDES; HIV | WARNER-LAMBERT COMPANY (US) | 1999-08-10 | — | — | US | disclosed |
| US-5840751-A | ADMINISTERING IN THE TREATMENT OF INFECTION OR DISEASE CAUSED BY A RETROVIRUS | WARNER-LAMBERT COMPANY (US) | 1998-11-24 | — | — | US | disclosed |
| US-5789440-A | 5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents | WARNER-LAMBERT COMPANY (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0729463-A1 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE DAVIS & COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| EP-0729464-A1 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995014012-A1 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1995-05-26 | — | — | WO | disclosed |
| WO-1995014011-A2 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1995-05-26 | — | — | WO | disclosed |