Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 1.00 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594139 | 0.88 | F10 (1.00) | F10PRSS12 | |
| SCHEMBL6589450 | 0.88 | F10 (1.00) | F10PRSS12TP53MAPTSMN1; SMN2 | |
| SCHEMBL6593442 | 0.88 | F10 (1.00) | F10PRSS12 | |
| SCHEMBL15292825 | 0.83 | F10 (0.71) | F10PRSS12TP53MAPTSMN1; SMN2 | |
| SCHEMBL6590441 | 0.83 | F10 (1.00) | F10PRSS12 | |
| SCHEMBL6590272 | 0.82 | F10 (1.00) | F10PRSS12 | |
| SCHEMBL6590377 | 0.82 | F10 (1.00) | F10PRSS12 | |
| SCHEMBL15283194 | 0.82 | PRSS12 (1.00) | F10PRSS12 | |
| SCHEMBL6591788 | 0.82 | F10 (0.88) | F10PRSS12TP53MAPTSMN1; SMN2 | |
| SCHEMBL6591396 | 0.81 | F10 (1.00) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040108-B1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AG (DE) | 2004-02-25 | — | — | EP | claimed |
| US-6380221-B1 | FOR THERAPY OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY | BERLEX LABORATORIES, INC. | 2002-04-30 | — | — | US | claimed |
| EP-1040108-B1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-6498185-B1 | ENZYME FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. | 2002-12-24 | — | — | US | disclosed |
| US-6380221-B1 | FOR THERAPY OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY | BERLEX LABORATORIES, INC. | 2002-04-30 | — | — | US | disclosed |
| US-6140351-A | FOR TREATING THROMBOSIS | BERLEX LABORATORIES, INC. (US) | 2000-10-31 | — | — | US | disclosed |