Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 18/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 12/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL670524 | 0.79 | PTGS2 (0.40) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7799595 | 0.78 | PTGS2 (0.51) | PTGS2PTGS1ALOX5 | |
| SCHEMBL5657768 | 0.78 | PTGS2 (0.39) | PTGS2PTGS1ALOX5 | |
| SCHEMBL15947273 | 0.78 | PTGS2 (0.39) | PTGS2PTGS1ALOX5 | |
| SCHEMBL13479401 | 0.78 | PTGS1 (0.39) | PTGS2PTGS1ALOX5 | |
| SCHEMBL25188734 | 0.78 | PTGS2 (0.39) | PTGS2PTGS1ALOX5 | |
| SCHEMBL15726927 | 0.77 | PTGS2 (0.57) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4613161 | 0.77 | PTGS2 (0.50) | PTGS2PTGS1ALOX5 | |
| SCHEMBL6669568 | 0.76 | PTGS2 (0.55) | PTGS2PTGS1ALOX5 | |
| SCHEMBL6153247 | 0.76 | PTGS2 (0.55) | PTGS2PTGS1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888323-B1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2004-05-19 | — | — | EP | disclosed |
| EP-0904272-B1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-0904272-A1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-03-31 | — | — | EP | disclosed |
| EP-0888323-A1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-01-07 | — | — | EP | disclosed |
| US-5686471-A | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents | THE PROCTER & GAMBLE COMPANY (US) | 1997-11-11 | — | — | US | disclosed |
| WO-1997028155-A1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1997-08-07 | — | — | WO | disclosed |
| WO-1997028147-A1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1997-08-07 | — | — | WO | disclosed |
| US-5618835-A | ANALGESICS | THE PROCTER & GAMBLE COMPANY (US) | 1997-04-08 | — | — | US | disclosed |