Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CDC7 | O00311 | 4/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594036 | 1.00 | KDM4E (0.50) | KDM4EHSD17B10ALDH1A1HPGDCDC7 | |
| SCHEMBL6598618 | 0.81 | KDM4E (0.57) | KDM4EHSD17B10ALDH1A1HPGDCDC7 | |
| SCHEMBL6598621 | 0.81 | KDM4E (0.57) | KDM4EHSD17B10ALDH1A1HPGDCDC7 | |
| SCHEMBL6665598 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1HPGDADORA2AADORA1 | |
| SCHEMBL6594202 | 0.79 | MAPT (0.42) | KDM4EALDH1A1HPGDLMNAPKM | |
| SCHEMBL6594197 | 0.79 | MAPT (0.42) | KDM4EALDH1A1HPGDLMNAPKM | |
| SCHEMBL6591213 | 0.76 | CDC7 (0.46) | KDM4EHSD17B10ALDH1A1HPGDCDC7 | |
| SCHEMBL6591217 | 0.76 | CDC7 (0.46) | KDM4EHSD17B10ALDH1A1HPGDCDC7 | |
| SCHEMBL6594838 | 0.76 | TNF (0.65) | KDM4EALDH1A1HPGDLMNACYP1A2 | |
| SCHEMBL6594835 | 0.76 | TNF (0.65) | KDM4EALDH1A1HPGDLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | claimed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | claimed |
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | disclosed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | disclosed |