Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594036 | 0.80 | KDM4E (0.50) | KDM4EMAPTCDK1GSK3BCDK5 | |
| SCHEMBL6594041 | 0.80 | KDM4E (0.50) | KDM4EMAPTCDK1GSK3BCDK5 | |
| SCHEMBL6666936 | 0.75 | KDM4E (0.42) | KDM4EMAPTCTSVCTSLHPGD | |
| SCHEMBL6666941 | 0.75 | KDM4E (0.42) | KDM4EMAPTCTSVCTSLHPGD | |
| SCHEMBL6594202 | 0.75 | MAPT (0.42) | KDM4EMAPTHPGDRAB9AALDH1A1 | |
| SCHEMBL6594197 | 0.75 | MAPT (0.42) | KDM4EMAPTHPGDRAB9AALDH1A1 | |
| SCHEMBL6665810 | 0.74 | TNF (0.64) | KDM4EMAPTCTSVCTSLCCNB2 | |
| SCHEMBL6663559 | 0.74 | POLB (0.37) | KDM4EMAPTCTSVCTSLCCNB2 | |
| SCHEMBL6594838 | 0.72 | TNF (0.65) | KDM4EMAPTHPGDRAB9AALDH1A1 | |
| SCHEMBL6594835 | 0.72 | TNF (0.65) | KDM4EMAPTHPGDRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | claimed |
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | disclosed |