Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TYMS | P04818 | 1/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.47 |
| ▸ | ITGAL | P20701 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27490972 | 1.00 | ELANE (0.64) | ELANETDP1CTRB1MAPTMEN1 | |
| SCHEMBL6593941 | 0.92 | ELANE (0.53) | ELANETDP1CTRB1MAPTITGB2 | |
| SCHEMBL27477556 | 0.92 | ELANE (0.53) | ELANETDP1CTRB1MAPTITGB2 | |
| SCHEMBL6499165 | 0.91 | ITGB2 (0.56) | ELANECTRB1MAPTMEN1KMT2A | |
| SCHEMBL6595086 | 0.82 | ELANE (0.74) | ELANECTRB1 | |
| SCHEMBL27477143 | 0.82 | ELANE (0.74) | ELANECTRB1 | |
| SCHEMBL10362846 | 0.78 | ELANE (1.00) | ELANECTRB1 | |
| SCHEMBL27478831 | 0.78 | ELANE (1.00) | ELANECTRB1 | |
| SCHEMBL6597882 | 0.78 | ELANE (0.70) | ELANECTRB1 | |
| SCHEMBL8545277 | 0.78 | MAPT (0.59) | MAPTMEN1KMT2AITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122245-B1 | 2-Amino-benzoxazinones for the treatment of viral infections | SEARLE & CO (US) | 2004-07-07 | — | — | EP | claimed |
| CN-1190963-A | 2-amino-benzoxanones for the treatment of viral infections | SEARLE & CO (US) | 1998-08-19 | — | — | CN | claimed |
| CN-1190963-A | 2-amino-benzoxanones for the treatment of viral infections | SEARLE & CO (US) | 1998-08-19 | — | — | CN | disclosed |