Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.56 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.56 |
| ▸ | ITGAL | P20701 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499165 | 0.86 | ITGB2 (0.56) | MAPTHPGDPKMHTTITGB2 | |
| SCHEMBL8549802 | 0.80 | MAPT (0.51) | MAPTHPGDPKMHTTMAPK1 | |
| SCHEMBL27490972 | 0.78 | ELANE (0.64) | MAPTITGB2ICAM1ITGALMEN1 | |
| SCHEMBL6594113 | 0.78 | ELANE (0.64) | MAPTITGB2ICAM1ITGALMEN1 | |
| SCHEMBL6593941 | 0.75 | ELANE (0.53) | MAPTITGB2ICAM1ITGALSMN1; SMN2 | |
| SCHEMBL27477556 | 0.75 | ELANE (0.53) | MAPTITGB2ICAM1ITGALSMN1; SMN2 | |
| SCHEMBL30971002 | 0.73 | ALOX15 (0.66) | MAPTITGB2ICAM1ITGALPOLB | |
| SCHEMBL8545278 | 0.73 | ELANE (0.47) | HSD17B10ALDH1A1LMNAUSP2 | |
| SCHEMBL8551382 | 0.73 | ELANE (0.47) | HSD17B10ALDH1A1LMNAUSP2 | |
| Acetyltryptophan SCHEMBL9603283 | 0.73 | ITGB2 (0.76) | MAPTITGB2ICAM1ITGALPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | claimed |
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | disclosed |