Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | TNF | P01375 | 3/20 | 0.58 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594494 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KDM4ETNFNOD1RAB9A | |
| SCHEMBL6595374 | 0.86 | KDM4E (0.61) | ALDH1A1KDM4ETNFNOD1RAB9A | |
| SCHEMBL6595378 | 0.86 | KDM4E (0.61) | ALDH1A1KDM4ETNFNOD1RAB9A | |
| SCHEMBL6593291 | 0.85 | KDM4E (0.64) | ALDH1A1KDM4ETNFNOD1RAB9A | |
| SCHEMBL6593293 | 0.85 | KDM4E (0.64) | ALDH1A1KDM4ETNFNOD1RAB9A | |
| SCHEMBL6594142 | 0.85 | KDM4E (0.63) | ALDH1A1KDM4ETNFNOD1RAB9A | |
| SCHEMBL6594146 | 0.85 | KDM4E (0.63) | ALDH1A1KDM4ETNFNOD1RAB9A | |
| SCHEMBL6591967 | 0.81 | MAPT (0.67) | ALDH1A1KDM4ETNFNOD1RAB9A | |
| SCHEMBL6590221 | 0.81 | KDM4E (0.58) | ALDH1A1KDM4ETNFNOD1RAB9A | |
| SCHEMBL6591971 | 0.81 | MAPT (0.67) | ALDH1A1KDM4ETNFNOD1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | claimed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | disclosed |