Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1726223 | 0.85 | MAPT (0.49) | BACE1PIM1KDM4EKMT2AMAPT | |
| SCHEMBL1723184 | 0.81 | KDM4E (0.66) | BACE1PIM1KDM4EKMT2AMMP2 | |
| SCHEMBL341567 | 0.79 | BACE1 (0.50) | BACE1PIM1KDM4EKMT2ACA1 | |
| SCHEMBL28337295 | 0.77 | KMT2A (0.47) | PIM1KDM4EKMT2AMAPTHDAC8 | |
| SCHEMBL3532312 | 0.76 | ALDH1A1 (0.39) | KDM4EKMT2AMAPTUSP2SMN1; SMN2 | |
| SCHEMBL16654015 | 0.75 | BACE1 (0.46) | BACE1PIM1KDM4EKMT2ACA1 | |
| SCHEMBL29496137 | 0.75 | BACE1 (0.46) | BACE1PIM1KDM4EKMT2AAR | |
| SCHEMBL18463763 | 0.72 | BACE1 (0.50) | BACE1PIM1KDM4EKMT2ACA1 | |
| SCHEMBL29496059 | 0.72 | GNE (0.55) | BACE1PIM1KDM4EMAPTLMNA | |
| SCHEMBL15228545 | 0.72 | GNE (0.55) | BACE1PIM1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |