Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593772 | 0.82 | AR (0.56) | L3MBTL1ALDH1A1LMNAMAPTPARP1 | |
| SCHEMBL6602046 | 0.79 | KDM4E (0.43) | ALDH1A1KDM4EPARP1NPSR1 | |
| SCHEMBL8888591 | 0.78 | ALDH1A1 (0.57) | L3MBTL1ALDH1A1LMNAMAPTGAA | |
| SCHEMBL5114852 | 0.78 | KDM4E (0.53) | L3MBTL1ALDH1A1LMNAMAPTGAA | |
| SCHEMBL26617566 | 0.78 | KDM4E (0.53) | L3MBTL1ALDH1A1LMNAMAPTGAA | |
| SCHEMBL30681975 | 0.78 | KDM4E (0.53) | L3MBTL1ALDH1A1LMNAMAPTGAA | |
| SCHEMBL31423182 | 0.78 | KDM4E (0.53) | L3MBTL1ALDH1A1LMNAMAPTGAA | |
| SCHEMBL2309931 | 0.76 | ALDH1A1 (0.57) | L3MBTL1ALDH1A1LMNAMAPTGAA | |
| SCHEMBL31345632 | 0.76 | ALDH1A1 (0.57) | L3MBTL1ALDH1A1LMNAMAPTGAA | |
| SCHEMBL6596943 | 0.75 | GRIA1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156044-B1 | 6-SUBSTITUTED HETEROQUINOLINECARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN SEIYAKU KK (JP) | 2004-08-25 | — | — | EP | disclosed |
| US-6562839-B1 | Effective for the therapy of disorder of cerebral nerve cells as antagonists against excitatory amino acid receptors | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-05-13 | — | — | US | disclosed |
| EP-1156044-A1 | 6-SUBSTITUTED HETEROQUINOLINECARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2001-11-21 | — | — | EP | disclosed |