Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592451 | 0.87 | KMT2A (0.47) | TSHRRECQLSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6592801 | 0.85 | LMNA (0.39) | CNR2MAPTPKMMDM2MEN1 | |
| SCHEMBL2583648 | 0.82 | CNR2 (0.46) | CNR2TSHRSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL18532593 | 0.82 | CNR2 (0.46) | CNR2TSHRSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL20426003 | 0.82 | CNR2 (0.46) | CNR2TSHRSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL2564896 | 0.82 | CNR2 (0.46) | CNR2TSHRSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL6592432 | 0.76 | TLR2 (0.44) | SIRT3SMN1; SMN2MAPTPKMCCR5 | |
| Oxalic Acid SCHEMBL30495310 | 0.76 | CNR2 (0.44) | CNR2TSHRSMN1; SMN2MAPTPKM | |
| SCHEMBL18532605 | 0.76 | CNR2 (0.43) | CNR2TSHRSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL18790107 | 0.76 | CNR2 (0.43) | CNR2TSHRSMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189883-B1 | SUBSTITUTED PYRROLIDINES AS CELL ADHESION INHIBITORS | AVENTIS PHARMA LTD (GB) | 2004-11-03 | — | — | EP | disclosed |
| EP-1189883-A2 | SUBSTITUTED PYRROLIDINES AS CELL ADHESION INHIBITORS | Aventis Pharma Limited (GB) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000068195-A2 | SUBSTITUTED PYRROLIDINES AS CELL ADHESION INHIBITORS | AVENTIS PHARMA LIMITED (GB) | 2000-11-16 | — | — | WO | disclosed |