Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 15/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055405 | 0.82 | ADAM17 (0.58) | ADAM17MMP3MMP2MMP13 | |
| Hydrochloric Acid SCHEMBL4054029 | 0.78 | ADAM17 (0.56) | ADAM17MMP3MMP2MMP13 | |
| SCHEMBL5887489 | 0.74 | ADAM17 (0.58) | ADAM17MMP3MMP13 | |
| SCHEMBL1504715 | 0.73 | ADAM17 (0.64) | ADAM17MMP3MMP2MMP13 | |
| SCHEMBL6596846 | 0.73 | ADAM17 (0.53) | ADAM17MMP3MMP2MMP13 | |
| SCHEMBL5887895 | 0.73 | ADAM17 (0.61) | ADAM17MMP3MMP2MMP13 | |
| SCHEMBL6632245 | 0.73 | ADAM17 (0.63) | ADAM17MMP3MMP2MMP13 | |
| SCHEMBL5887679 | 0.72 | ADAM17 (0.58) | ADAM17MMP3MMP2MMP13 | |
| SCHEMBL6291728 | 0.72 | ADAM17 (0.58) | ADAM17MMP3MMP2MMP13 | |
| SCHEMBL5887571 | 0.72 | ADAM17 (0.58) | ADAM17MMP3MMP2MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263756-B1 | BETA-AMINO ACID DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEASES AND TNF-ALPHA | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2004-02-25 | — | — | EP | disclosed |