Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 16/20 | 0.54 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6595376 | 0.82 | UTS2R (0.52) | UTS2RHRH3LTA4H | |
| SCHEMBL6597841 | 0.81 | UTS2R (0.65) | UTS2R | |
| SCHEMBL17152648 | 0.80 | SIGMAR1 (0.49) | HRH2HRH1HRH3 | |
| SCHEMBL6744737 | 0.77 | UTS2R (0.53) | UTS2RHRH3 | |
| SCHEMBL6741883 | 0.77 | UTS2R (0.53) | UTS2RHRH3 | |
| SCHEMBL6955647 | 0.76 | UTS2R (0.90) | UTS2R | |
| SCHEMBL6951628 | 0.76 | UTS2R (0.90) | UTS2R | |
| SCHEMBL6951621 | 0.76 | UTS2R (0.90) | UTS2R | |
| SCHEMBL6597273 | 0.76 | UTS2R (0.68) | UTS2R | |
| SCHEMBL17152225 | 0.75 | SIGMAR1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246619-B1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-10-20 | — | — | EP | disclosed |
| US-6514970-B1 | Pyrrolidines such as benzo(b)thiophene-2-carboxylic acid ((S)-1-((S)-1-(4-(1-benzyl-piperidin-4-yloxy)-3-chloro-benzyl)-pyrrolidin-3 -ylcarbamoyl)-3- methyl-butyl)-amide | SMITHKLINE BEECHAM CORPORATION | 2003-02-04 | — | — | US | disclosed |