Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 13/20 | 0.58 |
| ▸ | HTR1B | P28222 | 10/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR1F | P30939 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6598060 | 0.90 | HTR1D (0.55) | HTR1DHTR1BCHRM2DRD2HTR1A | |
| SCHEMBL6595208 | 0.89 | HTR1D (0.61) | HTR1DHTR1BCHRM2DRD2HTR1A | |
| SCHEMBL6596015 | 0.88 | HTR1D (0.63) | HTR1DHTR1BCHRM2DRD2HTR1A | |
| SCHEMBL6598083 | 0.87 | HTR1D (0.59) | HTR1DHTR1BCHRM2DRD2HTR1A | |
| SCHEMBL6595427 | 0.87 | HTR1D (0.59) | HTR1DHTR1BCHRM2DRD2HTR1A | |
| SCHEMBL6597296 | 0.86 | HTR1D (0.76) | HTR1DHTR1BCHRM2DRD2HTR1A | |
| SCHEMBL6595304 | 0.86 | HTR1D (0.59) | HTR1DHTR1BCHRM2DRD2HTR1A | |
| SCHEMBL6598851 | 0.86 | HTR1D (0.58) | HTR1DHTR1BCHRM2DRD2HTR1A | |
| SCHEMBL6597926 | 0.85 | HTR1D (0.71) | HTR1DHTR1BCHRM2DRD2HTR1A | |
| SCHEMBL6598475 | 0.84 | HTR1D (0.60) | HTR1DHTR1BCHRM2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305307-B1 | INDOLE DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS | LUNDBECK & CO AS H (DK) | 2004-05-06 | — | — | EP | claimed |