Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588333 | 0.95 | MALT1 (0.43) | MALT1ABCC9ABCC8KCNJ11MTNR1A | |
| SCHEMBL6590364 | 0.91 | MALT1 (0.45) | MALT1ABCC9ABCC8KCNJ11MTNR1A | |
| SCHEMBL4254830 | 0.91 | ABCC9 (0.50) | ABCC9ABCC8KCNJ11ALDH1A1POLB | |
| SCHEMBL6592437 | 0.91 | MALT1 (0.43) | MALT1ABCC9ABCC8KCNJ11MTNR1A | |
| SCHEMBL6591040 | 0.89 | MALT1 (0.43) | MALT1ABCC9ABCC8KCNJ11MTNR1A | |
| SCHEMBL6591893 | 0.86 | ABCC9 (0.48) | ABCC9ABCC8KCNJ11ALDH1A1POLB | |
| SCHEMBL6590717 | 0.86 | MALT1 (0.48) | MALT1MTNR1APOLBMAPTCA1 | |
| SCHEMBL6589529 | 0.85 | ABCC9 (0.49) | ABCC9ABCC8KCNJ11L3MBTL1ALDH1A1 | |
| SCHEMBL6592791 | 0.85 | ABCC9 (0.37) | ABCC9ABCC8KCNJ11L3MBTL1ALDH1A1 | |
| SCHEMBL6590513 | 0.83 | MALT1 (0.49) | MALT1MTNR1APOLBMAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842927-B1 | 3-Amido-chromanylsulfonyl(thio)ureas, process for their preparation, their use and medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-02-25 | — | — | EP | disclosed |
| EP-0842927-A1 | 3-Amido-chromanylsulfonyl(thio)ureas, process for their preparation, their use and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-05-20 | — | — | EP | disclosed |