Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 10/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 9/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358412 | 1.00 | ITGA4 (0.39) | ITGA4ITGB1MEN1KMT2AMAPT | |
| SCHEMBL14222075 | 0.93 | ITGA4 (0.39) | ITGA4ITGB1MEN1KMT2AMAPT | |
| SCHEMBL4672022 | 0.93 | ITGA4 (0.39) | ITGA4ITGB1MEN1KMT2AMAPT | |
| SCHEMBL4671706 | 0.93 | ITGA4 (0.46) | ITGA4ITGB1MEN1KMT2AMAPT | |
| SCHEMBL6515607 | 0.93 | ITGA4 (0.46) | ITGA4ITGB1MEN1KMT2AMAPT | |
| SCHEMBL6515595 | 0.93 | ITGA4 (0.46) | ITGA4ITGB1MEN1KMT2AMAPT | |
| SCHEMBL8360429 | 0.92 | ITGA4 (0.41) | ITGA4ITGB1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL4674500 | 0.92 | ITGA4 (0.45) | ITGA4ITGB1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL4674517 | 0.92 | ITGA4 (0.45) | ITGA4ITGB1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL4674506 | 0.92 | ITGA4 (0.45) | ITGA4ITGB1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414444-A1 | NOVEL IMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS VLA-4 ANTAGONISTS | Aventis Pharma Deutschland GmbH (DE) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003011288-A1 | NOVEL IMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS VLA-4 ANTAGONISTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-02-13 | — | — | WO | disclosed |