SCHEMBL659614

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL660445	0.99	JAK2 (0.60)	JAK2EGFRPRKD3PRKCGPRKCB
	SCHEMBL10192761	0.94	JAK2 (0.59)	JAK2EGFRPRKD3PRKCGPRKCB
	SCHEMBL10245770	0.91	JAK2 (0.62)	JAK2EGFRJAK3HDAC1HDAC6
	SCHEMBL10246683	0.91	JAK2 (0.61)	JAK2EGFRJAK3HDAC1HDAC6
	SCHEMBL10246893	0.89	JAK2 (0.64)	JAK2EGFRZAP70JAK3HDAC1
	SCHEMBL10246812	0.89	CDK2 (0.58)	JAK2EGFRPRKD3PRKCGPRKCB
	SCHEMBL10245501	0.89	PRKD3 (0.57)	JAK2EGFRPRKD3PRKCGPRKCB
	SCHEMBL10246390	0.89	JAK2 (0.59)	JAK2EGFRZAP70JAK3HDAC1
	SCHEMBL10245417	0.89	PRKD3 (0.56)	JAK2EGFRPRKD3PRKCGPRKCB
	SCHEMBL14755163	0.88	EGFR (0.54)	JAK2EGFRPRKD3PRKCGPRKCB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.