SCHEMBL6596291

SCHEMBL6596291

O[C@H]1CCCC[C@@H]1N1CCCCC1

nearest known ligand 0.80

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 11/20 0.72
CYP2D6 P10635 2/20 0.53
TSHR P16473 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2C9 P11712 1/20 0.53
SIGMAR1 Q99720 1/20 0.53
ALDH1A1 P00352 1/20 0.52
APEX1 P27695 1/20 0.52
BLM P54132 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6597981 1.00 SLC18A3 (0.72) SLC18A3CYP2D6TSHRSMN1; SMN2CYP1A2
SCHEMBL6597979 1.00 SLC18A3 (0.72) SLC18A3CYP2D6TSHRSMN1; SMN2CYP1A2
SCHEMBL10960265 1.00 SLC18A3 (0.72) SLC18A3CYP2D6TSHRSMN1; SMN2CYP1A2
SCHEMBL6597975 1.00 SLC18A3 (0.72) SLC18A3CYP2D6TSHRSMN1; SMN2CYP1A2
SCHEMBL6596292 1.00 SLC18A3 (0.72) SLC18A3CYP2D6TSHRSMN1; SMN2CYP1A2
SCHEMBL6593610 1.00 SLC18A3 (0.72) SLC18A3CYP2D6TSHRSMN1; SMN2CYP1A2
SCHEMBL8989808 1.00 SLC18A3 (0.72) SLC18A3CYP2D6TSHRSMN1; SMN2CYP1A2
SCHEMBL11346322 1.00 SLC18A3 (0.72) SLC18A3CYP2D6TSHRSMN1; SMN2CYP1A2
SCHEMBL11346290 1.00 SLC18A3 (0.72) SLC18A3CYP2D6TSHRSMN1; SMN2CYP1A2
SCHEMBL10960261 1.00 SLC18A3 (0.72) SLC18A3CYP2D6TSHRSMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179233-A1 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC COPOLYMERIZATION OF CONJUGATED DIENES AND LIQUID COPOLYMERS THEREOF ALBEMARLE CORPORATION (US) 2025-06-05 US disclosed
EP-4486808-A2 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC COPOLYMERIZATION OF CONJUGATED DIENES AND LIQUID COPOLYMERS THEREOF ALBEMARLE CORPORATION (US) 2025-01-08 EP disclosed
US-20240034825-A1 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC POLYMERIZATION OF CONJUGATED DIENES AND LIQUID POLYMERS THEREOF ALBEMARLE CORPORATION 2024-02-01 US disclosed
WO-2023168218-A2 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC COPOLYMERIZATION OF CONJUGATED DIENES AND LIQUID COPOLYMERS THEREOF ALBEMARLE CORPORATION (US) 2023-09-07 WO disclosed
EP-4208485-A1 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC POLYMERIZATION OF CONJUGATED DIENES AND LIQUID POLYMERS THEREOF ALBEMARLE CORPORATION (US) 2023-07-12 EP disclosed
US-8008342-B2 Ion channel modulating compounds and uses thereof CARDIOME PHARMA CORP. (CA) 2011-08-30 US disclosed
US-20110207730-A1 ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF CARDIOME PHARMA CORP. (CA) 2011-08-25 US disclosed
US-7875611-B2 (+)-trans-[2-(4-morpholinyl)-1-[2-(2-naphthoxy)ethoxy)]; (1R,2R)/(1S,2S)-2-[1,4-dioxa-7-azaspiro[4.4]non-7-yl]-1-(1-naphthenethoxy)cyclohexanecyclohexane; treatment of arrhythmia and the production of analgesia and local anesthesia CARDIOME PHARMA CORP. (CA) 2011-01-25 US disclosed
US-20100056603-A1 ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF CARDIOME PHARMA CORP. (CA) 2010-03-04 US disclosed
US-20100029639-A1 ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF CARDIOME PHARMA CORP. (CA) 2010-02-04 US disclosed
US-6060488-A ANTICARCINOGENIC AGENTS; POSTMENOPAUSAL CANCER OF BREASTS, UTERUS, CERVIX ELI LILLY AND COMPANY (US) 2000-05-09 US disclosed
US-6025382-A Antithrombotic diamines ELI LILLY AND COMPANY (US) 2000-02-15 US disclosed
WO-1999015521-A1 BENZOTHIOPHENES ELI LILLY AND COMPANY (US) 1999-04-01 WO disclosed
EP-0905132-A1 Benzothiophenes ELI LILLY AND COMPANY (US) 1999-03-31 EP disclosed
EP-0863755-A4 ANTITHROMBOTIC DIAMINES LILLY CO ELI (US) 1999-01-20 EP disclosed
EP-0863755-A1 ANTITHROMBOTIC DIAMINES ELI LILLY AND COMPANY (US) 1998-09-16 EP disclosed
WO-1997025033-A1 ANTITHROMBOTIC DIAMINES ELI LILLY AND COMPANY (US) 1997-07-17 WO disclosed
EP-0072620-B1 3-METHYLFLAVONE-8-CARBOXYLIC ACID ESTERS RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) 1985-12-04 EP disclosed
US-4550115-A ANTISPASMODIC, CALCIUM BLOCKER, ANESTHETIC, AND ANTINFLAMMATORY AG RECORDATI S.A., CHEMICAL & PHARMACEUTICAL COMPANY (CH) 1985-10-29 US disclosed
EP-0072620-A1 3-Methylflavone-8-carboxylic acid esters RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) 1983-02-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110207730-A1 ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF TRPV1, TRPA1, KCNN2 SLC18A3 208/4885CYP2D6 1182/4885TSHR 2898/4885
US-20100056603-A1 ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF TRPV1, TRPA1, KCNN2 SLC18A3 208/4885CYP2D6 1182/4885TSHR 2898/4885
US-20100029639-A1 ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF TRPV1, TRPA1, KCNN2 SLC18A3 208/4885CYP2D6 1182/4885TSHR 2898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.