Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 6/20 | 0.39 |
| ▸ | HTR2A | P28223 | 6/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28811244 | 0.98 | TSHR (0.41) | TSHRHRH1HTR2ASIGMAR1SMN1; SMN2 | |
| SCHEMBL2408107 | 0.93 | TSHR (0.44) | TSHRHRH1HTR2ASIGMAR1SMN1; SMN2 | |
| SCHEMBL22042223 | 0.91 | TSHR (0.50) | TSHRHRH1HTR2ASIGMAR1TAAR1 | |
| SCHEMBL3218900 | 0.84 | TSHR (0.48) | TSHRHRH1HTR2ATAAR1 | |
| SCHEMBL22042229 | 0.81 | TSHR (0.55) | TSHRHRH1HTR2ATAAR1 | |
| SCHEMBL7295713 | 0.81 | TSHR (0.41) | TSHRHRH1HTR2ASIGMAR1TAAR1 | |
| SCHEMBL8995497 | 0.81 | TSHR (0.41) | TSHRHRH1HTR2ASIGMAR1TAAR1 | |
| SCHEMBL4770684 | 0.81 | HRH1 (0.42) | TSHRHRH1HTR2ASIGMAR1TAAR1 | |
| SCHEMBL4306863 | 0.81 | SIGMAR1 (0.44) | TSHRHRH1HTR2ASIGMAR1POLB | |
| SCHEMBL9503361 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915867-B1 | THIENYLCYCLOHEXANE DERIVATIVES FOR THIENYLCYCLOHEXYL SYNTHESIS | SOD CONSEILS RECH APPLIC (FR) | 2004-10-06 | — | — | EP | disclosed |
| US-6107495-A | REACTING SPECIFIED 1-(2- OR 3-THIENYL) CYCLOHEXANES WITH A 1,5-DIHALOPENTANE TO FORM CYCLIC (THIENYLCYCLOHEXYL)AMINES SUCH AS 2-ALKYL-(3-THIENYL)CYCLOHEXYL PIPERIDINE; USE AS INTERMEDIATES TO RADIOACTIVE LABELLED MOLECULES | SOCIETE D'EXPANSION SCIENTIFIQUE EXPANSIA (FR) | 2000-08-22 | — | — | US | disclosed |
| EP-0915867-A1 | THIENYLCYCLOHEXANE DERIVATIVES FOR THIENYLCYCLOHEXYL SYNTHESIS | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003498-A1 | THIENYLCYCLOHEXANE DERIVATIVES FOR THIENYLCYCLOHEXYL SYNTHESIS | SOCIETE D'EXPANSION SCIENTIFIQUE EXPANSIA (FR) | 1998-01-29 | — | — | WO | disclosed |