Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 5/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7628527 | 0.99 | HTR3A (0.65) | HTR3A | |
| SCHEMBL17417624 | 0.92 | HTR3A (0.73) | HTR3A | |
| SCHEMBL7432371 | 0.86 | HTR3A (0.74) | HTR3A | |
| SCHEMBL6595864 | 0.85 | HTR3A (0.62) | HTR3A | |
| SCHEMBL6593770 | 0.85 | HTR3A (0.65) | HTR3A | |
| SCHEMBL7484664 | 0.84 | HTR3A (0.61) | HTR3A | |
| SCHEMBL6599886 | 0.84 | HTR3A (0.67) | HTR3A | |
| Iodide SCHEMBL7622185 | 0.84 | HTR3A (0.64) | HTR3A | |
| SCHEMBL6598243 | 0.84 | HTR3A (0.61) | HTR3A | |
| SCHEMBL7621226 | 0.84 | HTR3A (0.63) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888338-B1 | NOVEL SUBSTITUTED N-METHYL-N-(4-(4-(1H-BENZIMIDAZOL-2-YL) 1,4]DIAZEPAN-1-YL)-2-(ARYL)BUTYL)BENZAMIDES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | AVENTIS PHARMA INC (US) | 2004-11-17 | — | — | EP | disclosed |