Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | PRKCI | P41743 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.32 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CCNH | P51946 | 1/20 | 0.32 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 6/20 | 0.32 |
| ▸ | AKT2 | P31751 | 3/20 | 0.32 |
| ▸ | FPR1 | P21462 | 2/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SGK1 | O00141 | 2/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL6596649 | 1.00 | P2RY14 (0.34) | P2RY14CHRM1CHRM3PRKCICHRM2 | |
| Oxalic Acid SCHEMBL6596632 | 1.00 | P2RY14 (0.34) | P2RY14CHRM1CHRM3PRKCICHRM2 | |
| SCHEMBL6599237 | 0.93 | PRKCI (0.36) | CHRM1CHRM3PRKCICHRM2CHRM4 | |
| SCHEMBL6599236 | 0.93 | PRKCI (0.36) | CHRM1CHRM3PRKCICHRM2CHRM4 | |
| SCHEMBL6599232 | 0.93 | PRKCI (0.36) | CHRM1CHRM3PRKCICHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL6597105 | 0.70 | HTR2C (0.36) | P2RY14PRKCICDK7CCNHMNAT1 | |
| Hydrochloric Acid SCHEMBL6597110 | 0.70 | HTR2C (0.36) | P2RY14PRKCICDK7CCNHMNAT1 | |
| Hydrochloric Acid SCHEMBL6597102 | 0.70 | HTR2C (0.36) | P2RY14PRKCICDK7CCNHMNAT1 | |
| Hydrochloric Acid SCHEMBL6596577 | 0.70 | PRKCI (0.33) | CHRM1CHRM3PRKCICHRM2CHRM4 | |
| SCHEMBL6334203 | 0.69 | EED (0.37) | CHRM1CHRM3CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204660-B1 | SEROTONERGIC BENZOTHIOPHENES | LILLY CO ELI (US) | 2004-10-20 | — | — | EP | disclosed |