Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 8/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.31 |
| ▸ | CCNH | P51946 | 1/20 | 0.31 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599236 | 1.00 | PRKCI (0.36) | PRKCICDK7CCNHMNAT1NMT1 | |
| SCHEMBL6599232 | 1.00 | PRKCI (0.36) | PRKCICDK7CCNHMNAT1NMT1 | |
| Oxalic Acid SCHEMBL6596644 | 0.93 | P2RY14 (0.34) | PRKCICDK7CCNHMNAT1PRKCQ | |
| Oxalic Acid SCHEMBL6596649 | 0.93 | P2RY14 (0.34) | PRKCICDK7CCNHMNAT1PRKCQ | |
| Oxalic Acid SCHEMBL6596632 | 0.93 | P2RY14 (0.34) | PRKCICDK7CCNHMNAT1PRKCQ | |
| Hydrochloric Acid SCHEMBL6597105 | 0.75 | HTR2C (0.36) | PRKCICDK7CCNHMNAT1PRKCQ | |
| Hydrochloric Acid SCHEMBL6597110 | 0.75 | HTR2C (0.36) | PRKCICDK7CCNHMNAT1PRKCQ | |
| Hydrochloric Acid SCHEMBL6597102 | 0.75 | HTR2C (0.36) | PRKCICDK7CCNHMNAT1PRKCQ | |
| Hydrochloric Acid SCHEMBL6596577 | 0.75 | PRKCI (0.33) | PRKCIPRKCQCHRM1CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL6596636 | 0.75 | SLC6A2 (0.40) | PRKCINMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204660-B1 | SEROTONERGIC BENZOTHIOPHENES | LILLY CO ELI (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-1204660-A1 | SEROTONERGIC BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001009126-A1 | SEROTONERGIC BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |