SCHEMBL659665

SCHEMBL659665

C(=C/c1ccc2ccccc2n1)\c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 1.00
KDM4E B2RXH2 7/20 1.00
NPC1 O15118 7/20 1.00
LMNA P02545 5/20 1.00
PKM P14618 2/20 1.00
MAPT P10636 6/20 0.74
MEN1 O00255 5/20 0.74
KMT2A Q03164 5/20 0.74
L3MBTL1 Q9Y468 4/20 0.74
SMN1; SMN2 Q16637 4/20 0.74
ALDH1A1 P00352 1/20 0.74
MAPK1 P28482 2/20 0.68
CYSLTR2 Q9NS75 2/20 0.68
CYSLTR1 Q9Y271 2/20 0.68
RXFP1 Q9HBX9 1/20 0.68
HTT P42858 2/20 0.64
ECE2 P0DPD6 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
NFKB1 P19838 1/20 0.59
NFKB2 Q00653 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL659666 1.00 RAB9A (1.00) RAB9AKDM4ENPC1LMNAPKM
SCHEMBL30708719 1.00 RAB9A (1.00) RAB9AKDM4ENPC1LMNAPKM
SCHEMBL9170782 0.94 RAB9A (0.89) RAB9AKDM4ENPC1LMNAPKM
SCHEMBL9170780 0.94 RAB9A (0.89) RAB9AKDM4ENPC1LMNAPKM
Dimethylamine SCHEMBL11573560 0.93 RAB9A (0.86) RAB9AKDM4ENPC1LMNAPKM
Acetic Acid SCHEMBL10401609 0.90 KDM4E (0.81) RAB9AKDM4ENPC1LMNAPKM
Acetic Acid SCHEMBL10401610 0.90 KDM4E (0.81) RAB9AKDM4ENPC1LMNAPKM
Quinoline SCHEMBL28850584 0.90 RAB9A (0.81) RAB9AKDM4ENPC1LMNAPKM
SCHEMBL28443608 0.89 RAB9A (0.80) RAB9AKDM4ENPC1LMNAPKM
SCHEMBL29078431 0.89 RAB9A (0.80) RAB9AKDM4ENPC1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 795 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11692882-B2 Electrical component IRISS HOLDINGS LLC (US) 2023-07-04 US claimed
CN-110325618-B Thermochromic color-memory composition and thermochromic color-memory microcapsule pigment encapsulating same 百乐墨水株式会社 2023-01-10 CN claimed
US-11384247-B2 Thermochromic color-memory composition and thermochromic color-memory microcapsule pigment encapsulating the same KABUSHIKI KAISHA PILOT CORPORATION (JP) 2022-07-12 US claimed
EP-3587534-B1 THERMOCHROMIC COLOR MEMORIZING MICROCAPSULE PIGMENT ENCLOSING THERMOCHROMIC COLOR MEMORIZING COMPOSITION PILOT INK CO LTD (JP) 2021-10-06 EP claimed
US-20200284665-A1 ELECTRICAL COMPONENT GH Innovation Limited (GB) 2020-09-10 US claimed
EP-3695199-A1 AN ELECTRICAL COMPONENT GH Innovation Limited (GB) 2020-08-19 EP claimed
US-20200071532-A1 THERMOCHROMIC COLOR-MEMORY COMPOSITION AND THERMOCHROMIC COLOR-MEMORY MICROCAPSULE PIGMENT ENCAPSULATING THE SAME THE PILOT INK CO., LTD. (JP) 2020-03-05 US claimed
CN-107922831-B Thermochromic color-memory composition and thermochromic color-memory microcapsule pigment encapsulating same 百乐墨水株式会社 2019-12-17 CN claimed
EP-2431444-B1 THERMOCHROMIC COLOR-MEMORY COMPOSITION, AND THERMOCHROMIC COLOR-MEMORY MICROCAPSULE PIGMENT HAVING THE COMPOSITION ENCAPSULATED THEREIN PILOT INK CO LTD (JP) 2019-11-13 EP claimed
WO-2019073217-A1 AN ELECTRICAL COMPONENT GH Innovation Limited (GB) 2019-04-18 WO claimed
WO-2015074953-A1 ADHESIVE COMPOSITION COLLANO ADHESIVES AG (CH) 2015-05-28 WO claimed
EP-2873708-A1 Adhesive composition Collano Adhesives AG (CH) 2015-05-20 EP claimed
EP-1107063-B1 Photobleachable compounds containing photopolymerizable compositions for use in flexographic printing plates DU PONT (US) 2010-03-10 EP claimed
US-20050261336-A1 Use of quinoline derivatives with anti-integrase effect and applications thereof BIOALLIANCE PHARMA SA 2005-11-24 US claimed
US-6864039-B2 Such as naphthylvinyl-pyridine; for improved heat stability and image resolution E.I. DU PONT DE NEMOURS AND COMPANY (US) 2005-03-08 US claimed
US-20030219681-A1 Photobleachable compounds for use in flexographic printing plates CHENG LAP KIN (US) 2003-11-27 US claimed
EP-1107063-A1 Photobleachable compounds containing photopolymerizable compositions for use in flexographic printing plates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-06-13 EP claimed
EP-0399818-B1 Diarylstyrylquinoline diacids MERCK FROSST CANADA INC (CA) 1995-08-16 EP claimed
EP-0219308-B1 2-SUBSTITUTED QUINOLINES MERCK FROSST CANADA INC. (CA) 1991-10-23 EP claimed
US-4780393-A POLYMERIC BINDER, TERMINAL ETHYLENIC COMPOUND, PHOTOINITIATOR, LEVCO BASE OF TRIARYLMETHANE DYE AND PHOTOC ROMIC SPIRO-INDOLINO-BENZOPYRAN COMPOUND HOECHST AKTIENGESELLSCHAFT (DE) 1988-10-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050261336-A1 Use of quinoline derivatives with anti-integrase effect and applications thereof TYMP, CDK7, EIF2AK2 RAB9A 3320/4885KDM4E 1260/4885NPC1 1641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.