Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL219140 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL28313422 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL5110094 | 0.93 | — | — | |
| Bromide SCHEMBL1109772 | 0.88 | EPHX1 (0.52) | — | |
| Benzene SCHEMBL11408728 | 0.88 | L3MBTL1 (0.44) | — | |
| SCHEMBL178401 | 0.87 | — | — | |
| SCHEMBL9801180 | 0.84 | EPHX1 (0.55) | — | |
| SCHEMBL19574718 | 0.84 | EPHX1 (0.55) | — | |
| SCHEMBL9801057 | 0.84 | EPHX1 (0.55) | — | |
| Hydrochloric Acid SCHEMBL5110115 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118696933-A | Low-toxicity compound bactericide and preparation method and application thereof | 中国日用化学研究院有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-110478495-A | Target conjugate and its particle and preparation | TARVEDA THERAPEUTICS INC | 2019-11-22 | — | — | CN | disclosed |
| CN-106573077-B | Targeted conjugates and particles and formulations thereof | 塔弗达治疗有限公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-107759562-A | A kind of preparation method of hydrochloric acid revaprzan | 常州四药制药有限公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-106573077-A | Targeted conjugates and particles and formulations thereof | 塔弗达治疗有限公司 | 2017-04-19 | — | — | CN | disclosed |
| EP-0722936-B1 | FUSED PYRIDAZINE COMPOUND | EISAI CO LTD (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6218392-B1 | FOR THERAPY AND PROPHYLAXIS OF ISCHEMIC HEART DISEASES SUCH AS ANGINA PECTORIS, MYOCARDIAL INFARCT AND CHRONIC AND ACUTE CARDIAC FAILURE, PULMONARY HYPERTENSION, ARTERIOSCLEROSIS AND BRONCHIAL ASTHMA | EISAI CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-0722936-A1 | FUSED PYRIDAZINE COMPOUND | Eisai Co., Ltd. (JP) | 1996-07-24 | — | — | EP | disclosed |