Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 10/20 | 0.59 |
| ▸ | MAPK12 | P53778 | 10/20 | 0.59 |
| ▸ | MAPK11 | Q15759 | 10/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.58 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.58 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.58 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.58 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.58 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.58 |
| ▸ | FRK | P42685 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL6598276 | 0.96 | MAP4K4 (0.56) | MAPK13MAPK12MAPK11MAPK14MAP4K4 | |
| Butane SCHEMBL6590914 | 0.94 | MAP4K4 (0.55) | MAPK13MAPK12MAPK11MAPK14MAP4K4 | |
| SCHEMBL6844336 | 0.94 | MAPK14 (0.64) | MAPK13MAPK12MAPK11MAPK14MAP4K4 | |
| SCHEMBL5093475 | 0.90 | MAP4K4 (0.62) | MAPK13MAPK12MAPK11MAPK14MAP4K4 | |
| SCHEMBL10441604 | 0.88 | MAP4K4 (0.63) | MAPK13MAPK12MAPK11MAPK14MAP4K4 | |
| SCHEMBL10801666 | 0.87 | PRKD3 (0.62) | MAPK13MAPK12MAPK11MAPK14MAP4K4 | |
| SCHEMBL14002179 | 0.85 | PRKD3 (0.60) | MAPK13MAPK12MAPK11MAPK14MAP4K4 | |
| SCHEMBL14288457 | 0.85 | PRKD3 (0.60) | MAPK13MAPK12MAPK11MAPK14MAP4K4 | |
| SCHEMBL10441819 | 0.85 | PRKD3 (0.60) | MAPK13MAPK12MAPK11MAPK14MAP4K4 | |
| SCHEMBL10615042 | 0.85 | PTGS2 (0.59) | MAPK13MAPK12MAPK11MAPK14MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385828-A1 | COMPOUNDS OF THE FAMILY OF 3-ALKYL-(4,5 DIPHENY-IMIDAZOL-1-YL) AND THEIR USE AS SOOTHING AGENTS | L'OREAL (FR) | 2004-02-04 | — | — | EP | claimed |
| WO-2002085864-A1 | COMPOUNDS OF THE FAMILY OF 3-ALKYL-(4,5 DIPHENY-IMIDAZOL-1-YL) AND THEIR USE AS SOOTHING AGENTS | L'OREAL (FR) | 2002-10-31 | — | — | WO | claimed |
| EP-1385828-A1 | COMPOUNDS OF THE FAMILY OF 3-ALKYL-(4,5 DIPHENY-IMIDAZOL-1-YL) AND THEIR USE AS SOOTHING AGENTS | L'OREAL (FR) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002085864-A1 | COMPOUNDS OF THE FAMILY OF 3-ALKYL-(4,5 DIPHENY-IMIDAZOL-1-YL) AND THEIR USE AS SOOTHING AGENTS | L'OREAL (FR) | 2002-10-31 | — | — | WO | disclosed |