Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28289229 | 0.89 | SORD (0.44) | SORDKDM4EGPR3EGFRCYP1A2 | |
| SCHEMBL7074398 | 0.81 | KDM4E (0.37) | SORDKDM4EGPR3EGFRCYP1A2 | |
| SCHEMBL290894 | 0.79 | KDM4E (0.42) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL29756554 | 0.79 | KMT2A (0.44) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL30838793 | 0.79 | CYP1A2 (0.42) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL874900 | 0.79 | KMT2A (0.44) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL9934866 | 0.79 | KDM4E (0.42) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL9971234 | 0.79 | KDM4E (0.42) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL1514912 | 0.79 | CYP1A2 (0.42) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL2263641 | 0.79 | KDM4E (0.42) | KDM4EGPR3EGFRCYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028491-A | Fibroblast growth factor receptor inhibitor | 蓝图药品公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-106852143-B | Tricyclic triazolic compounds | 埃斯蒂维制药股份公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-105658642-B | Fibroblast growth factor receptor inhibitors | 蓝图药品公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-109705094-A | A kind of preparation method of pyridine quinazoline | 湖南速博生物技术有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-109526220-A | Tetrahydropyrimidinodiazepine and tetrahydropyridodiazepine compounds for the treatment of pain and pain-related conditions | 埃斯特维制药股份公司 | 2019-03-26 | — | — | CN | disclosed |
| CN-106432252-B | A kind of benzo carbazole derivative and the organic electroluminescence device using the derivative | 上海和辉光电有限公司 | 2018-11-30 | — | — | CN | disclosed |
| CN-105218476-B | A kind of preparation method for treating lung-cancer medicament | 上海天慈生物谷生物工程有限公司 | 2018-03-13 | — | — | CN | disclosed |
| CN-107750404-A | The Organic Light Emitting Diode of different substrates compound is included in the first and second electron transfer layers | 诺瓦尔德股份有限公司 | 2018-03-02 | — | — | CN | disclosed |
| CN-105418516-B | A kind of quinazoline compounds and preparation method thereof | 信阳师范学院 | 2018-03-02 | — | — | CN | disclosed |
| CN-107210374-A | Include the Organic Light Emitting Diode of the electron transfer layer with different substrates compound | 诺瓦尔德股份有限公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-106852143-A | Tricyclic triazolic compounds | 埃斯蒂维实验室股份有限公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-102459249-A | Benzoxazepines based p13k/mt0r inhibitors against proliferative diseases | EXELIXIS INC | 2012-05-16 | — | — | CN | disclosed |
| EP-1385833-A1 | TRIAZINYL AMIDE DERIVATIVES AS ANGIOGENESIS INHIBITORS | Amgen Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002083654-A1 | TRIAZINYL AMIDE DERIVATIVES AS ANGIOGENESIS INHIBITORS | AMGEN INC. (US) | 2002-10-24 | — | — | WO | disclosed |