Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6597904 | 1.00 | CDC7 (0.48) | CDC7KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL6598618 | 0.79 | KDM4E (0.57) | CDC7KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL6598621 | 0.79 | KDM4E (0.57) | CDC7KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL6591217 | 0.79 | CDC7 (0.46) | CDC7KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL6591213 | 0.79 | CDC7 (0.46) | CDC7KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL6593751 | 0.79 | CDC7 (0.45) | CDC7KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL6593747 | 0.79 | CDC7 (0.45) | CDC7KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL6592328 | 0.76 | TNF (0.71) | CDC7KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL6592329 | 0.76 | TNF (0.71) | CDC7KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL6594018 | 0.76 | ECE2 (0.39) | RAB9ATNFNOD1MAPK1ECE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | claimed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | claimed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | disclosed |