Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE2 | P0DPD6 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 8/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 2/20 | 0.34 |
| ▸ | DDO | Q99489 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594020 | 1.00 | ECE2 (0.39) | ECE2ARMEN1KMT2AHSP90AA1 | |
| SCHEMBL6597902 | 0.76 | CDC7 (0.48) | ECE2LMNAMAPK1RAB9ATNF | |
| SCHEMBL6597904 | 0.76 | CDC7 (0.48) | ECE2LMNAMAPK1RAB9ATNF | |
| SCHEMBL6592151 | 0.75 | ALDH1A1 (0.50) | MEN1KMT2AHSP90AA1MAPTGAA | |
| SCHEMBL12042897 | 0.73 | KDM4E (0.49) | MEN1KMT2AMAPTLMNARAB9A | |
| SCHEMBL6597807 | 0.73 | ERN1 (0.45) | MEN1KMT2AHSP90AA1MAPTGAA | |
| SCHEMBL6597809 | 0.73 | ERN1 (0.45) | MEN1KMT2AHSP90AA1MAPTGAA | |
| SCHEMBL6590163 | 0.71 | TNF (0.64) | RAB9ATNFNOD1 | |
| SCHEMBL6590161 | 0.71 | TNF (0.64) | RAB9ATNFNOD1 | |
| SCHEMBL6593006 | 0.67 | MAPT (0.49) | MEN1KMT2AHSP90AA1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | claimed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | claimed |
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | disclosed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | disclosed |