Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL266607 | 0.86 | CA12 (0.57) | TSHRALDH1A1TDP1MAPTMEN1 | |
| Dimethylamine SCHEMBL2105293 | 0.81 | CA12 (0.54) | TSHRALDH1A1TDP1MAPTMEN1 | |
| SCHEMBL26605090 | 0.79 | MAPT (0.47) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL12778678 | 0.79 | MAPT (0.47) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL31217544 | 0.78 | MEN1 (0.55) | TSHRALDH1A1TDP1MAPTMEN1 | |
| SCHEMBL10717733 | 0.77 | CA12 (0.52) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL6509784 | 0.77 | SMN1; SMN2 (0.49) | ALDH1A1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL3057669 | 0.76 | KDM4E (0.63) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL9678208 | 0.76 | MEN1 (0.45) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL26605095 | 0.76 | CYP2A6 (0.51) | ALDH1A1MAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156803-A4 | LACTAM INHIBITORS OF FXa AND METHOD | BRISTOL MYERS SQUIBB CO (US) | 2004-03-17 | — | — | EP | disclosed |
| US-6544981-B2 | Anticoagulants, cardiovascular disorders | BRISTOL-MYERS SQUIBB COMPANY | 2003-04-08 | — | — | US | disclosed |
| EP-1294716-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | Bristol-Myers Squibb Company (US) | 2003-03-26 | — | — | EP | disclosed |
| US-20020025957-A1 | Lactam inhibitors of factor Xa and method | BRISTOL-MYERS SQUIBB COMPANY | 2002-02-28 | — | — | US | disclosed |
| WO-2001096331-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |
| EP-1156803-A1 | LACTAM INHIBITORS OF FXa AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6297233-B1 | Lactam inhibitors of FXa and method | BRISTOL-MYERS SQUIBB COMPANY | 2001-10-02 | — | — | US | disclosed |
| WO-2000047207-A1 | LACTAM INHIBITORS OF FXa AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-08-17 | — | — | WO | disclosed |
| US-5158964-A | Benzoxazole sulfonamide anti-arrhythmic agents | PFIZER INC. (US) | 1992-10-27 | — | — | US | disclosed |
| US-5130334-A | INDANE SULFONAMIDE ANTI-ARRHYTHMIC AGENTS | PFIZER INC. (US) | 1992-07-14 | — | — | US | disclosed |
| CN-1015804-B | METHOD FOR PREPARATION OF SULPHONIC ACID AMIDE COMPOUND FOR ANTIARRHYTHMIC AGENT | PFIZER LTD (GB) | 1992-03-11 | — | — | CN | disclosed |
| US-5055473-A | QUINOLINYL SULFONAMIDE ANTI-ARRHYTHMIC AGENTS AND USE THEREAS | PFIZER INC. (US) | 1991-10-08 | — | — | US | disclosed |
| US-4956382-A | TERTIARY AMINE HETEROCYCLIC SULFONAMIDES | PFIZER INC. (US) | 1990-09-11 | — | — | US | disclosed |
| EP-0286277-B1 | ANTIARRYTHMIC AGENTS | Pfizer Limited (GB) | 1990-06-20 | — | — | EP | disclosed |
| EP-0281254-B1 | ANTIARRYTHMIC AGENTS | Pfizer Limited (GB) | 1990-01-17 | — | — | EP | disclosed |
| CN-1038451-A | Antiarrhythmics | PFIZER LTD (GB) | 1990-01-03 | — | — | CN | disclosed |
| US-4829071-A | Quinolyl substituted indane sulfonamides and their use as anti-arrhythmic agents | PFIZER INC. (US) | 1989-05-09 | — | — | US | disclosed |
| EP-0286277-A1 | Antiarrythmic agents | Pfizer Limited (GB) | 1988-10-12 | — | — | EP | disclosed |
| EP-0281254-A1 | Antiarrythmic agents | Pfizer Limited (GB) | 1988-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020025957-A1 | Lactam inhibitors of factor Xa and method | F9, F7, F11 | TSHR 1530/4885ALDH1A1 2640/4885TDP1 2167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.