Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6313890 | 0.82 | KDM4E (0.50) | SLC9A1KMT2AMEN1PTGDR2MAPT | |
| SCHEMBL6599323 | 0.77 | SLC22A12 (0.40) | KMT2AMAPTLMNACYP3A4CYP2C9 | |
| SCHEMBL3713540 | 0.75 | SLC9A1 (0.60) | SLC9A1KMT2AMEN1MAPTHTT | |
| Hydrochloric Acid SCHEMBL6314064 | 0.74 | SLC9A1 (0.59) | SLC9A1KMT2AMEN1MAPTHTT | |
| SCHEMBL3713536 | 0.72 | SLC9A1 (0.42) | SLC9A1KMT2AMEN1LMNAMALT1 | |
| SCHEMBL5245224 | 0.72 | KDM4E (0.55) | KMT2AMEN1MAPTLMNACYP3A4 | |
| Hydrochloric Acid SCHEMBL6314052 | 0.71 | SLC9A1 (0.41) | SLC9A1KMT2AMEN1LMNAMALT1 | |
| SCHEMBL6312201 | 0.71 | SLC9A1 (0.45) | SLC9A1KMT2AMEN1PTGDR2MAPT | |
| SCHEMBL2308927 | 0.70 | FABP5 (0.53) | KMT2AMEN1MAPTHTTLMNA | |
| SCHEMBL20028704 | 0.68 | SLC9A1 (0.47) | SLC9A1KMT2AMEN1PTGDR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056729-B1 | N-[(SUBSTITUTED FIVE-MEMBERED DI- OR TRIAZA DIUNSATURATED RING)CARBONYL]GUANIDINE DERIVATIVES FOR THE TREATMENT OF ISCHEMIA | PFIZER PROD INC (US) | 2004-12-29 | — | — | EP | claimed |