SCHEMBL6598148

SCHEMBL6598148

COc1cc(Cc2c(-c3ccc(OCCO)cc3)sc3cc(OCc4ccccc4)ccc23)ccc1CN1CCOCC1

nearest known ligand 0.63

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F2 P00734 17/20 0.63
UBE2N P61088 1/20 0.43
PDCD1 Q15116 1/20 0.41
CD274 Q9NZQ7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6598562 0.92 F2 (0.74) F2UBE2N
SCHEMBL7989741 0.90 F2 (0.70) F2CD274
SCHEMBL7774216 0.89 F2 (0.76) F2
SCHEMBL7774213 0.89 F2 (0.76) F2
SCHEMBL6597991 0.88 F2 (0.69) F2
SCHEMBL6172092 0.86 F2 (0.73) F2CD274
SCHEMBL6172249 0.86 ESR1 (0.50) F2
SCHEMBL7972046 0.84 F2 (0.66) F2
SCHEMBL6173777 0.84 F2 (0.67) F2CD274
SCHEMBL6599613 0.84 F2 (0.58) F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0980366-B1 ANTITHROMBOTIC AGENTS LILLY CO ELI (US) 2004-06-09 EP disclosed
US-6271227-B1 ANTICOAGULANTS ELI LILLY AND COMPANY 2001-08-07 US disclosed