Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.74 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6597991 | 0.94 | F2 (0.69) | F2 | |
| SCHEMBL6598148 | 0.92 | F2 (0.63) | F2UBE2N | |
| SCHEMBL7775907 | 0.91 | F2 (0.74) | F2UBE2NESR1ESR2 | |
| SCHEMBL6595899 | 0.90 | F2 (0.91) | F2ESR1ESR2 | |
| SCHEMBL6594628 | 0.89 | F2 (0.75) | F2 | |
| SCHEMBL7774213 | 0.88 | F2 (0.76) | F2 | |
| SCHEMBL7774216 | 0.88 | F2 (0.76) | F2 | |
| SCHEMBL7774139 | 0.88 | F2 (0.68) | F2ESR1ESR2 | |
| SCHEMBL7768104 | 0.88 | F2 (0.68) | F2ESR1ESR2 | |
| SCHEMBL7989741 | 0.88 | F2 (0.70) | F2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-B1 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 2004-12-15 | — | — | EP | disclosed |
| US-6265575-B1 | THROMBIN INHIBITORS | ELI LILLY AND COMPANY | 2001-07-24 | — | — | US | disclosed |
| US-6025382-A | Antithrombotic diamines | ELI LILLY AND COMPANY (US) | 2000-02-15 | — | — | US | disclosed |
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |