Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6597213 | 0.91 | GRIA1 (0.42) | FPR2GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6595172 | 0.88 | GRIA1 (0.48) | FPR2RORCGRIA1GRIA2GRIA3 | |
| SCHEMBL6596766 | 0.86 | RORC (0.40) | RORCGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6596000 | 0.79 | GRIA1 (0.56) | FPR2GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6600127 | 0.78 | GRIA1 (0.47) | FPR2GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6598356 | 0.78 | GRIA1 (0.42) | GRIA1GRIA2GRIA3GRIA4DYRK1A | |
| SCHEMBL6596186 | 0.77 | GRIA1 (0.43) | GRIA1GRIA2GRIA3GRIA4HSP90AA1 | |
| SCHEMBL6598164 | 0.75 | GRIA1 (0.49) | RORCGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6598978 | 0.73 | GRIA1 (0.47) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL6599634 | 0.73 | MAPT (0.37) | KMT2AMEN1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156044-B1 | 6-SUBSTITUTED HETEROQUINOLINECARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN SEIYAKU KK (JP) | 2004-08-25 | — | — | EP | disclosed |
| US-6562839-B1 | Effective for the therapy of disorder of cerebral nerve cells as antagonists against excitatory amino acid receptors | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-05-13 | — | — | US | disclosed |
| EP-1156044-A1 | 6-SUBSTITUTED HETEROQUINOLINECARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2001-11-21 | — | — | EP | disclosed |