Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 9/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6081081 | 0.90 | PTGER1 (0.45) | PTGER1RXRARXRBRXRGPTGER4 | |
| SCHEMBL6592323 | 0.87 | MCL1 (0.48) | PTGER1RXRARXRBRXRGMCL1 | |
| SCHEMBL6672382 | 0.86 | PTGER1 (0.43) | PTGER1RXRARXRBRXRGPTGER4 | |
| SCHEMBL6593903 | 0.85 | P2RY14 (0.46) | PTGER1RXRARXRBRXRGMCL1 | |
| SCHEMBL6596767 | 0.84 | MRGPRX4 (0.47) | PTGER1MCL1MRGPRX4 | |
| SCHEMBL6590520 | 0.84 | MRGPRX4 (0.47) | PTGER1MCL1MRGPRX4DHODH | |
| SCHEMBL6592207 | 0.81 | MRGPRX4 (0.44) | PTGER1MCL1MRGPRX4 | |
| SCHEMBL6602356 | 0.81 | MRGPRX4 (0.42) | PTGER1MCL1MRGPRX4 | |
| SCHEMBL31389237 | 0.80 | ALOX15 (0.64) | PTGER1MCL1MRGPRX4 | |
| SCHEMBL2908552 | 0.80 | ALOX15 (0.64) | PTGER1MCL1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |