Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 16/20 | 0.81 |
| ▸ | CCR3 | P51677 | 16/20 | 0.81 |
| ▸ | CCR1 | P32246 | 2/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.52 |
| ▸ | DRD2 | P14416 | 4/20 | 0.52 |
| ▸ | DRD4 | P21917 | 4/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane SCHEMBL6598467 | 1.00 | HRH1 (0.81) | HRH1CCR3CCR1KCNH2DRD2 | |
| Cyclopentane SCHEMBL6598773 | 1.00 | HRH1 (0.81) | HRH1CCR3CCR1KCNH2DRD2 | |
| SCHEMBL6075194 | 0.91 | HRH1 (0.78) | HRH1CCR3CCR1KCNH2DRD2 | |
| SCHEMBL6074255 | 0.90 | HRH1 (0.80) | HRH1CCR3CCR1KCNH2DRD2 | |
| SCHEMBL18841190 | 0.90 | HRH1 (1.00) | HRH1CCR3CCR1KCNH2DRD2 | |
| SCHEMBL6075302 | 0.89 | HRH1 (0.75) | HRH1CCR3CCR1KCNH2DRD2 | |
| SCHEMBL6075311 | 0.89 | HRH1 (0.75) | HRH1CCR3CCR1KCNH2DRD2 | |
| SCHEMBL6074823 | 0.89 | HRH1 (0.78) | HRH1CCR3CCR1KCNH2DRD2 | |
| SCHEMBL6075260 | 0.88 | HRH1 (0.77) | HRH1CCR3CCR1KCNH2DRD2 | |
| SCHEMBL6075050 | 0.87 | HRH1 (0.75) | HRH1CCR3CCR1KCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299356-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-11 | — | — | EP | claimed |