Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | C1R | P00736 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594806 | 0.84 | ELANE (0.65) | ELANEKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL6567148 | 0.81 | ELANE (0.55) | ELANEKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL6988517 | 0.80 | TTR (0.57) | KMT2AALDH1A1MEN1KDM4EPARP1 | |
| SCHEMBL12959615 | 0.75 | ELANE (0.73) | ELANEKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL321784 | 0.74 | ELANE (0.62) | ELANEKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL15251669 | 0.74 | ELANE (0.61) | ELANEKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL7000142 | 0.74 | ELANE (0.58) | ELANECSNK2A1KMT2AALDH1A1MEN1 | |
| SCHEMBL6565079 | 0.71 | MAPT (0.54) | ELANEKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL272287 | 0.70 | ELANE (0.81) | ELANEKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL15292882 | 0.69 | ESR1 (0.58) | CSNK2A1KMT2AALDH1A1MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301509-B1 | MULTIFUNCTIONAL COUPLING AGENTS WITH CYCLIC IMINOESTER AND IMINOETHER GROUPS, METHOD FOR PRODUCING THE SAME AND USE THEREOF | INST POLYMERFORSCHUNG DRESDEN (DE) | 2004-10-06 | — | — | EP | disclosed |