SCHEMBL659864

SCHEMBL659864

CCCCCCCCCCCCc1ccccc1OOc1ccccc1.[Na]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.50
THRB P10828 1/20 0.50
PPARA Q07869 3/20 0.48
LIPG Q9Y5X9 1/20 0.47
ALOX5 P09917 1/20 0.46
PTGS2 P35354 1/20 0.46
PPARG P37231 2/20 0.46
HRH1 P35367 2/20 0.44
TSHR P16473 1/20 0.43
HTR2A P28223 2/20 0.42
MLNR O43193 1/20 0.42
NR1I2 O75469 1/20 0.42
ESR1 P03372 1/20 0.42
NR3C1 P04150 1/20 0.42
PGR P06401 1/20 0.42
ADRB2 P07550 1/20 0.42
CHRM2 P08172 1/20 0.42
ADRB1 P08588 1/20 0.42
HTR1A P08908 1/20 0.42
ADRA2A P08913 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL659863 0.97 THRA (0.50) THRATHRBPPARALIPGALOX5
SCHEMBL1859695 0.85 HRH1 (0.57) THRATHRBPPARALIPGALOX5
SCHEMBL196865 0.85 HRH1 (0.57) THRATHRBPPARALIPGALOX5
SCHEMBL11055223 0.85 HRH1 (0.57) THRATHRBPPARALIPGALOX5
SCHEMBL321170 0.83 HRH1 (0.59) THRATHRBPPARALIPGALOX5
SCHEMBL20895821 0.83 HRH1 (0.59) THRATHRBPPARALIPGALOX5
SCHEMBL6552750 0.83 HRH1 (0.59) THRATHRBPPARALIPGALOX5
SCHEMBL8016071 0.83 HRH1 (0.59) THRATHRBPPARALIPGALOX5
SCHEMBL407448 0.83 HRH1 (0.59) THRATHRBPPARALIPGALOX5
SCHEMBL6369360 0.83 HRH1 (0.59) THRATHRBPPARALIPGALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10752037-B2 Lithographic imaging and printing without defects of electrostatic origin MARK ANDY, INC. (US) 2020-08-25 US disclosed
US-20160332472-A1 LITHOGRAPHIC IMAGING AND PRINTING WITHOUT DEFECTS OF ELECTROSTATIC ORIGIN VERICO TECHNOLOGY LLC 2016-11-17 US disclosed
EP-2796927-B1 Lithographic printing plate precursors EASTMAN KODAK CO (US) 2016-01-13 EP disclosed
EP-2531353-B1 LITHOGRAPHIC IMAGING AND PRINTING WITHOUT DEFECTS OF ELECTROSTATIC ORIGIN PRESSTEK INC (US) 2015-09-23 EP disclosed
EP-2217970-B1 IMAGEABLE ELEMENTS WITH COMPONENTS HAVING 1H-TETRAZOLE GROUPS EASTMAN KODAK CO (US) 2015-06-03 EP disclosed
US-8993213-B2 Positive-working lithographic printing plate EASTMAN KODAK COMPANY (US) 2015-03-31 US disclosed
US-20150072289-A9 POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE BANK OF AMERICA, N.A., AS AGENT 2015-03-12 US disclosed
US-8936902-B2 Positive-working imageable elements and method of use EASTMAN KODAK COMPANY (US) 2015-01-20 US disclosed
US-8875629-B2 Ablation-type lithographic imaging with enhanced debris removal PRESSTEK, INC. (US) 2014-11-04 US disclosed
EP-2796927-A1 Lithographic printing plate precursors Eastman Kodak Company (US) 2014-10-29 EP disclosed
US-20090253069-A1 IMAGEABLE ELEMENTS USEFUL FOR WATERLESS PRINTING QUALEX INC. 2009-10-08 US disclosed
US-20090246698-A1 METHODS FOR IMAGING AND PROCESSING NEGATIVE-WORKING IMAGEABLE ELEMENTS EASTMAN KODAK COMPANY 2009-10-01 US disclosed
US-20090197206-A1 METHOD OF MAKING IMAGES USING FRESH PROCESSING SOLUTION EASTMAN KODAK COMPANY 2009-08-06 US disclosed
WO-2009094170-A1 METHOD OF MAKING IMAGES USING FRESH PROCESSING SOLUTION EASTMAN KODAK COMPANY (US) 2009-07-30 WO disclosed
WO-2009094120-A1 METHOD OF MAKING LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY (US) 2009-07-30 WO disclosed
US-20090186301-A1 METHOD OF MAKING LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY 2009-07-23 US disclosed
WO-2009073098-A1 IMAGEABLE ELEMENTS WITH COMPONENTS HAVING 1H-TETRAZOLE GROUPS EASTMAN KODAK COMPANY (US) 2009-06-11 WO disclosed
US-20090142702-A1 METHODS OF USING VIOLET-SENSITIVE IMAGEABLE ELEMENTS EASTMAN KODAK COMPANY 2009-06-04 US disclosed
US-20090142695-A1 IMAGEABLE ELEMENTS WITH COMPONENTS HAVING 1H-TETRAZOLE GROUPS BANK OF AMERICA, N.A., AS AGENT 2009-06-04 US disclosed
US-20090098482-A1 METHODS FOR IMAGING AND PROCESSING NEGATIVE-WORKING IMAGEABLE ELEMENTS LASER PACIFIC MEDIA CORPORATION 2009-04-16 US disclosed