Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 5/20 | 0.49 |
| ▸ | TACR3 | P29371 | 5/20 | 0.49 |
| ▸ | TRPV4 | Q9HBA0 | 15/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6394399 | 0.87 | TACR2 (0.57) | TACR2TACR3TRPV4OPRM1 | |
| Hydrochloric Acid SCHEMBL6399854 | 0.86 | TACR2 (0.57) | TACR2TACR3TRPV4OPRM1 | |
| SCHEMBL5203685 | 0.82 | TACR2 (0.57) | TACR2TACR3TRPV4OPRM1 | |
| SCHEMBL5202474 | 0.81 | TACR3 (0.59) | TACR2TACR3TRPV4OPRM1 | |
| SCHEMBL2373330 | 0.76 | TRPV4 (0.72) | TACR2TACR3TRPV4OPRM1 | |
| Hydrochloric Acid SCHEMBL5733490 | 0.75 | TRPV4 (0.71) | TACR2TACR3TRPV4OPRM1 | |
| SCHEMBL5945353 | 0.75 | TRPV4 (0.63) | TACR2TACR3TRPV4OPRM1 | |
| SCHEMBL5945435 | 0.75 | TRPV4 (0.59) | TACR2TACR3TRPV4OPRM1 | |
| SCHEMBL6393346 | 0.75 | TRPV4 (0.58) | TACR2TACR3TRPV4OPRM1 | |
| SCHEMBL5945404 | 0.74 | TRPV4 (0.62) | TACR2TACR3TRPV4OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377555-A1 | NOVEL COMPOUNDS | GlaxoSmithKline S.p.A. (IT) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002083645-A1 | NOVEL COMPOUNDS | GLAXOSMITHKLINE S.P.A. (IT) | 2002-10-24 | — | — | WO | disclosed |