Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.51 |
| ▸ | FNTB | P49356 | 5/20 | 0.51 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6596847 | 0.93 | FNTA (0.49) | FNTAFNTBPGGT1BCYP3A4GAA | |
| SCHEMBL6598190 | 0.92 | FNTA (0.52) | FNTAFNTBPGGT1BCYP3A4GAA | |
| SCHEMBL4955195 | 0.85 | FNTA (0.60) | FNTAFNTBPGGT1BCYP3A4KMT2A | |
| SCHEMBL6599881 | 0.83 | FNTA (0.39) | FNTAFNTBPGGT1BCYP3A4KMT2A | |
| SCHEMBL6600381 | 0.82 | FNTA (0.41) | FNTAFNTBPGGT1BCYP3A4GAA | |
| SCHEMBL6601970 | 0.81 | FNTA (0.41) | FNTAFNTBPGGT1BCYP3A4GAA | |
| SCHEMBL6599899 | 0.81 | FNTA (0.42) | FNTAFNTBPGGT1BCYP3A4GAA | |
| SCHEMBL6598941 | 0.78 | FNTA (0.73) | FNTAFNTBPGGT1BCYP3A4GAA | |
| SCHEMBL6977268 | 0.77 | FNTA (0.59) | FNTAFNTBPGGT1BCYP3A4KMT2A | |
| SCHEMBL6599696 | 0.74 | FNTA (0.55) | FNTAFNTBPGGT1BCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169320-B1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2004-09-22 | — | — | EP | claimed |
| EP-1169320-B1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2004-09-22 | — | — | EP | disclosed |
| US-6511978-B1 | For treating cancer, restenosis, atherosclerosis or viral infections | LG LIFE SCIENCES, LTD. (KR) | 2003-01-28 | — | — | US | disclosed |