Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.41 |
| ▸ | FNTB | P49356 | 7/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601970 | 0.92 | FNTA (0.41) | FNTAFNTBPGGT1BCYP3A4ALDH1A1 | |
| SCHEMBL6599881 | 0.90 | FNTA (0.39) | FNTAFNTBPGGT1BCYP3A4ALDH1A1 | |
| SCHEMBL6598190 | 0.89 | FNTA (0.52) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6599899 | 0.84 | FNTA (0.42) | FNTAFNTBPGGT1BCYP3A4ALDH1A1 | |
| SCHEMBL6598939 | 0.82 | FNTA (0.51) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6596847 | 0.81 | FNTA (0.49) | FNTAFNTBPGGT1BCYP3A4MAPT | |
| SCHEMBL6600150 | 0.78 | FNTA (0.38) | FNTAFNTBPGGT1BCYP3A4ALDH1A1 | |
| SCHEMBL4955195 | 0.77 | FNTA (0.60) | FNTAFNTBPGGT1BCYP3A4ALDH1A1 | |
| SCHEMBL6978530 | 0.77 | FNTA (0.52) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6977268 | 0.77 | FNTA (0.59) | FNTAFNTBPGGT1BCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169320-B1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2004-09-22 | — | — | EP | disclosed |
| US-6511978-B1 | For treating cancer, restenosis, atherosclerosis or viral infections | LG LIFE SCIENCES, LTD. (KR) | 2003-01-28 | — | — | US | disclosed |