Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 1.00 |
| ▸ | HTR1D | P28221 | 1/20 | 0.74 |
| ▸ | HTR7 | P34969 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29708061 | 0.85 | HTR1A (1.00) | HTR1AHTR1D | |
| SCHEMBL6597327 | 0.85 | HTR1A (1.00) | HTR1AHTR1D | |
| SCHEMBL6597158 | 0.82 | HTR1A (1.00) | HTR1AHTR1DHTR7 | |
| SCHEMBL8302958 | 0.82 | HTR1A (0.74) | HTR1AHTR1DHTR7 | |
| Hydrochloric Acid SCHEMBL6597536 | 0.81 | HTR1A (0.73) | HTR1AHTR1DHTR7 | |
| Hydrochloric Acid SCHEMBL6598848 | 0.81 | HTR1A (0.87) | HTR1AHTR1DHTR7 | |
| SCHEMBL6599536 | 0.81 | HTR1A (1.00) | HTR1AHTR1DHTR7 | |
| Hydrochloric Acid SCHEMBL6598674 | 0.81 | HTR1A (0.98) | HTR1AHTR1DHTR7 | |
| SCHEMBL6601390 | 0.81 | HTR1A (0.75) | HTR1AHTR1DHTR7 | |
| SCHEMBL6618280 | 0.80 | HTR1A (0.71) | HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008594-B1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA LAB (ES) | 2004-03-17 | — | — | EP | claimed |
| US-6262056-B1 | TREATING ANXIETY OR DEPRESSION | VITA-INVEST, SA (ES) | 2001-07-17 | — | — | US | claimed |
| EP-1008594-A1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA-INVEST, S.A. (ES) | 2000-06-14 | — | — | EP | claimed |
| EP-1008594-B1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA LAB (ES) | 2004-03-17 | — | — | EP | disclosed |
| US-6262056-B1 | TREATING ANXIETY OR DEPRESSION | VITA-INVEST, SA (ES) | 2001-07-17 | — | — | US | disclosed |
| EP-1008594-A1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA-INVEST, S.A. (ES) | 2000-06-14 | — | — | EP | disclosed |