Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 5/20 | 0.45 |
| ▸ | HTR7 | P34969 | 5/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.44 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.44 |
| ▸ | IDH2 | P48735 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5356341 | 1.00 | KMT2A (0.48) | KMT2ATDP1HTR1AHTR7DRD2 | |
| SCHEMBL5356347 | 1.00 | KMT2A (0.48) | KMT2ATDP1HTR1AHTR7DRD2 | |
| SCHEMBL5359940 | 0.88 | ALDH1A1 (0.55) | KMT2ATDP1DRD2HTR2ADRD3 | |
| SCHEMBL5366823 | 0.88 | STS (0.45) | KMT2ATDP1HTR1AHTR7STS | |
| SCHEMBL5366806 | 0.88 | ALDH1A1 (0.55) | KMT2ATDP1DRD2HTR2ADRD3 | |
| SCHEMBL5359944 | 0.88 | ALDH1A1 (0.55) | KMT2ATDP1DRD2HTR2ADRD3 | |
| SCHEMBL5366825 | 0.88 | STS (0.45) | KMT2ATDP1HTR1AHTR7STS | |
| SCHEMBL5363218 | 0.88 | KDM4E (0.44) | KMT2ATDP1KDM4ERECQLSMN1; SMN2 | |
| SCHEMBL5363211 | 0.88 | KDM4E (0.44) | KMT2ATDP1KDM4ERECQLSMN1; SMN2 | |
| SCHEMBL5374241 | 0.87 | ALDH1A1 (0.48) | KMT2AHTR1AHTR7DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317425-B1 | RESORCINOL DERIVATIVES | PFIZER PROD INC (US) | 2004-11-03 | — | — | EP | disclosed |