Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6598526 | 0.86 | MKNK1 (0.38) | TSHRMEN1KMT2AALDH1A1MKNK1 | |
| SCHEMBL6590472 | 0.73 | MAPK1 (0.50) | TSHRKMT2AGAAMAPK1MKNK1 | |
| SCHEMBL10735469 | 0.70 | TDP1 (0.43) | TSHRMAPK1LMNATDP1KDM4E | |
| SCHEMBL11140162 | 0.70 | ASAH1 (0.47) | TSHRLMNATDP1 | |
| SCHEMBL8792548 | 0.67 | TDP1 (0.46) | TSHRMEN1KMT2AMAPK1LMNA | |
| SCHEMBL6530090 | 0.67 | TDP1 (0.46) | MAPK1LMNATDP1KDM4E | |
| SCHEMBL10977722 | 0.65 | MAPT (0.51) | GSK3AGSK3BTSHRMEN1KMT2A | |
| SCHEMBL31228668 | 0.65 | GSK3A (0.53) | GSK3AGSK3BTSHRMEN1KMT2A | |
| SCHEMBL7844966 | 0.65 | HSD17B10 (0.41) | GSK3AGSK3BTSHRMEN1KMT2A | |
| SCHEMBL11451311 | 0.64 | TDP1 (0.46) | TSHRMAPK1LMNATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201664-B1 | BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2004-09-08 | — | — | EP | disclosed |
| US-6593323-B1 | Benzimidazole compound inhibitory action of forming of macrophages and is useful as an active ingredient of a medicament for preventive and/or therapeutic treatment of arteriosclerosis, which is represented by the formula (I): | FUJI PHOTO FILM CO., LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1201664-A1 | BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 2002-05-02 | — | — | EP | disclosed |