Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL699486 | 0.89 | LMNA (0.49) | MAPK1FGFR1SRCDRD2DRD4 | |
| SCHEMBL6598526 | 0.77 | MKNK1 (0.38) | MKNK1HTR7TSHRLMNAPOLB | |
| SCHEMBL6871616 | 0.74 | TDP1 (0.69) | MAPK1DRD2DRD4DRD3MKNK1 | |
| SCHEMBL6599113 | 0.73 | GSK3A (0.39) | MAPK1MKNK1TSHRLMNAKDM4E | |
| SCHEMBL10735469 | 0.73 | TDP1 (0.43) | MAPK1TSHRLMNAPOLBKDM4E | |
| SCHEMBL11140162 | 0.73 | ASAH1 (0.47) | DRD2TSHRLMNANPSR1 | |
| SCHEMBL8792548 | 0.70 | TDP1 (0.46) | MAPK1DRD2TSHRLMNAKMT2A | |
| SCHEMBL6530090 | 0.70 | TDP1 (0.46) | MAPK1LMNAPOLBKDM4ENPC1 | |
| SCHEMBL28794766 | 0.68 | MAPK1 (0.60) | MAPK1MKNK1LMNAKDM4E | |
| SCHEMBL12831026 | 0.67 | POLB (0.71) | FGFR1POLBKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815455-B1 | ANTIFOAM AGENTS OF MACROPHAGES; PREVENTING ARTERIOSCLEROSIS | FUJI PHOTO FILM CO., LTD. (JP) | 2004-11-09 | — | — | US | disclosed |
| EP-1197487-B1 | BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2004-01-14 | — | — | EP | disclosed |
| EP-1197487-A1 | BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME | Fuji Photo Film Co., Ltd. (JP) | 2002-04-17 | — | — | EP | disclosed |